Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET

Calcium (Ca(2+)) and 3’,5’-cyclic adenosine monophosphate (cAMP) play a critical role for cardiac excitation-contraction-coupling. Both second messengers are known to interact with each other, for example via Ca(2+)-dependent modulation of phosphodiesterase 1 (PDE1) and adenylyl cyclase 5/6 (AC 5/6)...

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Publicado en:PLoS One
Autores principales: Sprenger, Julia U., Bork, Nadja I., Herting, Jonas, Fischer, Thomas H., Nikolaev, Viacheslav O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145230/
https://ncbi.nlm.nih.gov/pubmed/27930744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167974
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