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Vertical collapse of a cytolysin prepore moves its transmembrane β-hairpins to the membrane
Perfringolysin O (PFO) is a prototype of the large family of pore-forming cholesterol-dependent cytolysins (CDCs). A central enigma of the cytolytic mechanism of the CDCs is that their membrane-spanning β-hairpins (the transmembrane amphipathic β-hairpins (TMHs)) appear to be ∼40 Å too far above the...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514522/ https://ncbi.nlm.nih.gov/pubmed/15297878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600350 |
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