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Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation

A number of proteins accumulate in the anaphase spindle midzone, but the interaction and precise role of these proteins in midzone organization remain obscure. Here, we found that the microtubule-bundling protein PRC1 bound separately to the three motor proteins, KIF4, MKLP1 and CENP-E, but not to t...

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Main Authors: Kurasawa, Yasuhiro, Earnshaw, William C, Mochizuki, Yuko, Dohmae, Naoshi, Todokoro, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC514520/
https://ncbi.nlm.nih.gov/pubmed/15297875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600347
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