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IL-15 independent maintenance of tissue resident and boosted effector memory CD8 T cells

IL-15 regulates central (T(CM)) and effector (T(EM)) memory CD8 T cell homeostatic proliferation, maintenance and longevity. Consequently, IL-15 availability hypothetically defines the carrying capacity for total memory CD8 T cells within the host. In conflict with this hypothesis, previous observat...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Schenkel, Jason M., Fraser, Kathryn A., Casey, Kerry A., Beura, Lalit K., Pauken, Kristen E., Vezys, Vaiva, Masopust, David
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145194/
https://ncbi.nlm.nih.gov/pubmed/27001957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502337
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