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Model of Turnover Kinetics in the Lamellipodium: Implications of Slow- and Fast-Diffusing Capping Protein and Arp2/3 Complex

Cell protrusion through polymerization of actin filaments at the leading edge of motile cells may be influenced by spatial gradients of diffuse actin and regulators. Here we study the distribution of two of the most important regulators, capping protein and Arp2/3 complex, which regulate actin polym...

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Detalhes bibliográficos
Publicado no:Phys Biol
Main Authors: McMillen, Laura M., Vavylonis, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144926/
https://ncbi.nlm.nih.gov/pubmed/27922825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/13/6/066009
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