Ages at menarche- and menopause-related genetic variants in relation to terminal duct lobular unit involution in normal breast tissue

PURPOSE: Reduced levels of terminal duct lobular unit (TDLU) involution, as reflected by higher numbers of TDLUs and acini per TDLU, have been associated with higher breast cancer risk. Younger age at menarche and older age at menopause have been previously related to lower levels of TDLU involution...

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Veröffentlicht in:Breast Cancer Res Treat
Hauptverfasser: Oh, Hannah, Bodelon, Clara, Palakal, Maya, Chatterjee, Nilanjan, Sherman, Mark E., Linville, Laura, Geller, Berta M., Vacek, Pamela M., Weaver, Donald L., Chicoine, Rachael E., Papathomas, Daphne, Patel, Deesha A., Xiang, Jackie, Clare, Susan E., Visscher, Daniel W., Mies, Carolyn, Hewitt, Stephen M., Brinton, Louise A., Storniolo, Anna Maria V., He, Chunyan, Garcia-Closas, Montserrat, Chanock, Stephen J., Gierach, Gretchen L., Figueroa, Jonine D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144736/
https://ncbi.nlm.nih.gov/pubmed/27342457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-016-3859-z
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