Folic acid-decorated polyamidoamine dendrimer mediates selective uptake and high expression of genes in head and neck cancer cells

AIM: Folic acid (FA)-decorated polyamidoamine dendrimer G4 (G4-FA) was synthesized and studied for targeted delivery of genes to head and neck cancer cells expressing high levels of folate receptors (FRs). METHODS: Cellular uptake, targeting specificity, cytocompatibility and transfection efficiency...

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Detaylı Bibliyografya
Yayımlandı:Nanomedicine (Lond)
Asıl Yazarlar: Xu, Leyuan, Kittrell, Shannon, Yeudall, W Andrew, Yang, Hu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Future Medicine Ltd 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144492/
https://ncbi.nlm.nih.gov/pubmed/27781559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2016-0244
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