Large-scale characterization of HeLa cell nuclear phosphoproteins

Determining the site of a regulatory phosphorylation event is often essential for elucidating specific kinase–substrate relationships, providing a handle for understanding essential signaling pathways and ultimately allowing insights into numerous disease pathologies. Despite intense research effort...

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Autors principals: Beausoleil, Sean A., Jedrychowski, Mark, Schwartz, Daniel, Elias, Joshua E., Villén, Judit, Li, Jiaxu, Cohn, Martin A., Cantley, Lewis C., Gygi, Steven P.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514446/
https://ncbi.nlm.nih.gov/pubmed/15302935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404720101
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