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A unified approach to polyene macrolides: Synthesis of candidin and nystatin polyols

Polyene macrolide antibiotics are naturally occurring antifungal agents. Members of this class include amphotericin B, which has been used widely to treat systemic fungal infections. A general synthetic strategy has been devised to prepare polyol chains associated with the polyene macrolides. Cyanoh...

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Autores principales: Kadota, Isao, Hu, Yueqing, Packard, Garrick K., Rychnovsky, Scott D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC514422/
https://ncbi.nlm.nih.gov/pubmed/15192147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401552101
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