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Synthesis of antimicrofilament marine macrolides: Synthesis and configurational assignment of a C(5)–C(16) degradation fragment of reidispongiolide A
Reidispongiolide A is a representative member of the sphinxolide/reidispongiolide group of cytotoxic 26-membered macrolides of marine origin. By interacting with actin in the cell cytoskeleton, the reidispongiolides and sphinxolides are potent microfilament destabilizing agents that represent a prom...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514421/ https://ncbi.nlm.nih.gov/pubmed/15201432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401548101 |
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