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Synthesis of antimicrofilament marine macrolides: Synthesis and configurational assignment of a C(5)–C(16) degradation fragment of reidispongiolide A

Reidispongiolide A is a representative member of the sphinxolide/reidispongiolide group of cytotoxic 26-membered macrolides of marine origin. By interacting with actin in the cell cytoskeleton, the reidispongiolides and sphinxolides are potent microfilament destabilizing agents that represent a prom...

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Detalhes bibliográficos
Main Authors: Paterson, Ian, Britton, Robert, Ashton, Kate, Knust, Henner, Stafford, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514421/
https://ncbi.nlm.nih.gov/pubmed/15201432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401548101
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