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Subchronic perfluorooctanesulfonate (PFOS) exposure induces elevated mutant frequency in an in vivo λ transgenic medaka mutation assay

Perfluorooctanesulfonate (PFOS) has been widely detected in the environment, wildlife and humans, but few studies have ever examined its mutagenic effect in vivo. In the present study, we use a transgenic fish model, the λ transgenic medaka, to evaluate the potential mutagenicity of PFOS in vivo fol...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Yuanhong, Hu, Wei, Huang, Changjiang, Hua, Shushan, Wei, Qihao, Bai, Chenglian, Chen, Jiangfei, Norris, Michelle B., Winn, Richard, Yang, Dongren, Dong, Qiaoxiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144067/
https://ncbi.nlm.nih.gov/pubmed/27929129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38466
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