Subchronic perfluorooctanesulfonate (PFOS) exposure induces elevated mutant frequency in an in vivo λ transgenic medaka mutation assay

Perfluorooctanesulfonate (PFOS) has been widely detected in the environment, wildlife and humans, but few studies have ever examined its mutagenic effect in vivo. In the present study, we use a transgenic fish model, the λ transgenic medaka, to evaluate the potential mutagenicity of PFOS in vivo fol...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chen, Yuanhong, Hu, Wei, Huang, Changjiang, Hua, Shushan, Wei, Qihao, Bai, Chenglian, Chen, Jiangfei, Norris, Michelle B., Winn, Richard, Yang, Dongren, Dong, Qiaoxiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144067/
https://ncbi.nlm.nih.gov/pubmed/27929129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38466
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