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Inhibition of PKR protects against H(2)O(2)-induced injury on neonatal cardiac myocytes by attenuating apoptosis and inflammation

Reactive oxygenation species (ROS) generated from reperfusion results in cardiac injury through apoptosis and inflammation, while PKR has the ability to promote apoptosis and inflammation. The aim of the study was to investigate whether PKR is involved in hydrogen peroxide (H(2)O(2)) induced neonata...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Wang, Yongyi, Men, Min, Xie, Bo, Shan, Jianggui, Wang, Chengxi, Liu, Jidong, Zheng, Hui, Yang, Wengang, Xue, Song, Guo, Changfa
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144063/
https://ncbi.nlm.nih.gov/pubmed/27929137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38753
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