Inhibition of PKR protects against H(2)O(2)-induced injury on neonatal cardiac myocytes by attenuating apoptosis and inflammation

Reactive oxygenation species (ROS) generated from reperfusion results in cardiac injury through apoptosis and inflammation, while PKR has the ability to promote apoptosis and inflammation. The aim of the study was to investigate whether PKR is involved in hydrogen peroxide (H(2)O(2)) induced neonata...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Wang, Yongyi, Men, Min, Xie, Bo, Shan, Jianggui, Wang, Chengxi, Liu, Jidong, Zheng, Hui, Yang, Wengang, Xue, Song, Guo, Changfa
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144063/
https://ncbi.nlm.nih.gov/pubmed/27929137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38753
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