Inhibition of PKR protects against H(2)O(2)-induced injury on neonatal cardiac myocytes by attenuating apoptosis and inflammation

Reactive oxygenation species (ROS) generated from reperfusion results in cardiac injury through apoptosis and inflammation, while PKR has the ability to promote apoptosis and inflammation. The aim of the study was to investigate whether PKR is involved in hydrogen peroxide (H(2)O(2)) induced neonata...

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Publicado no:Sci Rep
Main Authors: Wang, Yongyi, Men, Min, Xie, Bo, Shan, Jianggui, Wang, Chengxi, Liu, Jidong, Zheng, Hui, Yang, Wengang, Xue, Song, Guo, Changfa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144063/
https://ncbi.nlm.nih.gov/pubmed/27929137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38753
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