Functional connectivity changes resemble patterns of pTDP-43 pathology in amyotrophic lateral sclerosis

‘Resting-state’ fMRI allows investigation of alterations in functional brain organization that are associated with an underlying pathological process. We determine whether abnormal connectivity in amyotrophic lateral sclerosis (ALS) in a priori-defined intrinsic functional connectivity networks, acc...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Schulthess, Ines, Gorges, Martin, Müller, Hans-Peter, Lulé, Dorothée, Del Tredici, Kelly, Ludolph, Albert C., Kassubek, Jan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144012/
https://ncbi.nlm.nih.gov/pubmed/27929102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38391
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