A proteolytic modification of AIM promotes its renal excretion

Apoptosis inhibitor of macrophage (AIM, encoded by cd5l) is a multi-functional circulating protein that has a beneficial role in the regulation of a broad range of diseases, some of which are ameliorated by AIM administration in mice. In blood, AIM is stabilized by association with IgM pentamers and...

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Publicat a:Sci Rep
Autors principals: Yamazaki, Tomoko, Sugisawa, Ryoichi, Hiramoto, Emiri, Takai, Ryosuke, Matsumoto, Ayaka, Senda, Yoshie, Nakashima, Katsuhiko, Nelson, Peter S., Lucas, Jared M., Morgan, Andrew, Li, Zhenghua, Yamamura, Ken-ichi, Arai, Satoko, Miyazaki, Toru
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144010/
https://ncbi.nlm.nih.gov/pubmed/27929116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38762
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