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Structural analysis of the bipartite DNA-binding domain of Tc3 transposase bound to transposon DNA
The bipartite DNA-binding domain of Tc3 transposase, Tc3A, was crystallized in complex with its transposon recognition sequence. In the structure the two DNA-binding domains form structurally related helix–turn–helix (HTH) motifs. They both bind to the major groove on a single DNA oligomer, separate...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514390/ https://ncbi.nlm.nih.gov/pubmed/15304566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh770 |
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