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Structural analysis of the bipartite DNA-binding domain of Tc3 transposase bound to transposon DNA

The bipartite DNA-binding domain of Tc3 transposase, Tc3A, was crystallized in complex with its transposon recognition sequence. In the structure the two DNA-binding domains form structurally related helix–turn–helix (HTH) motifs. They both bind to the major groove on a single DNA oligomer, separate...

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Bibliografiset tiedot
Päätekijät: Watkins, Stephan, van Pouderoyen, Gertie, Sixma, Titia K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC514390/
https://ncbi.nlm.nih.gov/pubmed/15304566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh770
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