Benefits of Hormone Therapy Estrogens Depend on Estrogen Type: 17β-Estradiol and Conjugated Equine Estrogens Have Differential Effects on Cognitive, Anxiety-Like, and Depressive-Like Behaviors and Increase Tryptophan Hydroxylase-2 mRNA Levels in Dorsal Raphe Nucleus Subregions

Decreased serotonin (5-HT) function is associated with numerous cognitive and affective disorders. Women are more vulnerable to these disorders and have a lower rate of 5-HT synthesis than men. Serotonergic neurons in the dorsal raphe nucleus (DRN) are a major source of 5-HT in the forebrain and pla...

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Dettagli Bibliografici
Pubblicato in:Front Neurosci
Autori principali: Hiroi, Ryoko, Weyrich, Giulia, Koebele, Stephanie V., Mennenga, Sarah E., Talboom, Joshua S., Hewitt, Lauren T., Lavery, Courtney N., Mendoza, Perla, Jordan, Ambra, Bimonte-Nelson, Heather A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143618/
https://ncbi.nlm.nih.gov/pubmed/28008302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00517
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