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Estrogen decreases 5-HT(1B) autoreceptor mRNA in selective subregion of rat dorsal raphe nucleus: inverse association between gene expression and anxiety behavior in the open field

We have recently shown that estrogen decreases anxiety and increases expression of tryptophan hydroxylase-2 (TPH2), the rate-limiting enzyme for serotonin synthesis. However, the effects of estrogen on serotonin release and reuptake may also affect the overall availability of serotonin in the forebr...

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Detalhes bibliográficos
Main Authors: Hiroi, Ryoko, Neumaier, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667128/
https://ncbi.nlm.nih.gov/pubmed/19049819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.10.016
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