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Initiator tRNA genes template the 3′ CCA end at high frequencies in bacteria

BACKGROUND: While the CCA sequence at the mature 3′ end of tRNAs is conserved and critical for translational function, a genetic template for this sequence is not always contained in tRNA genes. In eukaryotes and Archaea, the CCA ends of tRNAs are synthesized post-transcriptionally by CCA-adding enz...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Ardell, David H., Hou, Ya-Ming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143459/
https://ncbi.nlm.nih.gov/pubmed/27927177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3314-x
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