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Distinct kinetic determinants for the stepwise CCA addition to tRNA

The universally conserved CCA sequence is present at the 3′ terminal 74–76 positions of all active tRNA molecules as a functional tag to participate in ribosome protein synthesis. The CCA enzyme catalyzes CCA synthesis in three sequential steps of nucleotide addition at rapid and identical rates. Ho...

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Detalhes bibliográficos
Main Authors: Kim, Sangbumn, Liu, Cuiping, Halkidis, Konstantine, Gamper, Howard B., Hou, Ya-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743048/
https://ncbi.nlm.nih.gov/pubmed/19696158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1669109
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