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TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK–STAT signaling pathway

We have previously observed the downregulation of TMEM2 in the liver tissue of patients with chronic hepatitis B virus (HBV) infection and in HepG2.2.15 cells with HBV genomic DNA. In the present study, we investigated the role and mechanism of TMEM2 in HepG2 and HepG2.2.15 during HBV infection HepG...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhu, X, Xie, C, Li, Y-m, Huang, Z-l, Zhao, Q-y, Hu, Z-x, Wang, P-p, Gu, Y-r, Gao, Z-l, Peng, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143376/
https://ncbi.nlm.nih.gov/pubmed/27253403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.146
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