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TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK–STAT signaling pathway

We have previously observed the downregulation of TMEM2 in the liver tissue of patients with chronic hepatitis B virus (HBV) infection and in HepG2.2.15 cells with HBV genomic DNA. In the present study, we investigated the role and mechanism of TMEM2 in HepG2 and HepG2.2.15 during HBV infection HepG...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Zhu, X, Xie, C, Li, Y-m, Huang, Z-l, Zhao, Q-y, Hu, Z-x, Wang, P-p, Gu, Y-r, Gao, Z-l, Peng, L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143376/
https://ncbi.nlm.nih.gov/pubmed/27253403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.146
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