AB317. SPR-44 Pharmacological activation of individual KCNQ channel subtypes in detrusor smooth muscle represents a promising novel approach for overactive bladder treatment

OBJECTIVE: Our recent studies have demonstrated voltage-gated KCNQ channels (KCNQ1-KCNQ5) as key regulators of detrusor smooth muscle (DSM) function. Despite emerging developments, the physiological role of individual KCNQ channel subtypes remains less clear. Here, we utilized the novel compound ML-...

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Publicado no:Transl Androl Urol
Main Authors: Provence, Aaron, Angoli, Damiano, Petkov, Georgi V.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
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Abstract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143272/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s317
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