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Genetic markers predict primary non-response and durable response to anti-TNF biologic therapies in Crohn’s disease
BACKGROUND: One-fifth of patients with Crohn’s Disease (CD) are primary non-responders (PNR) to anti-tumor necrosis factor (anti-TNF) therapy, and an estimated 10–15% will fail therapy annually. Little is known about the genetics of response to anti-TNF therapy. The aim of our study was to identify...
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| 發表在: | Am J Gastroenterol |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5143156/ https://ncbi.nlm.nih.gov/pubmed/27596696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2016.408 |
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