The P2 receptor antagonist PPADS abrogates LPS-induced neutrophil migration in the murine air pouch via inhibition of MIP-2 and KC production

In this work, we show that P2 nucleotide receptors control lipopolysaccharide (LPS)-induced neutrophil migration in the mouse air pouch model. Neutrophil infiltration in LPS-treated air pouches was reduced by the intravenous (iv) administration of the non-selective P2 receptor antagonist PPADS but n...

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Publicat a:Mol Immunol
Autors principals: Kukulski, Filip, Ben Yebdri, Fethia, Bahrami, Fariborz, Lévesque, Sébastien A., Martín-Satué, Mireia, Sévigny, Jean
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142838/
https://ncbi.nlm.nih.gov/pubmed/19889460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.09.037
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