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Extracellular ATP and P2 receptors are required for IL-8 to induce neutrophil migration
The chemokine interleukin 8 (IL-8) is a major chemoattractant for human neutrophils. Here, we demonstrate novel evidence that IL-8-induced neutrophil chemotaxis requires a concurrent activation of P2 receptors, most likely the P2Y(2) which is dominantly expressed in these cells. Indeed, the migratio...
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| Publicado no: | Cytokine |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5140287/ https://ncbi.nlm.nih.gov/pubmed/19303321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2009.02.011 |
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