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Inferring cell state transition dynamics from lineage trees and endpoint single-cell measurements

As they proliferate, living cells undergo transitions between specific molecularly and developmentally distinct states. Despite the functional centrality of these transitions in multicellular organisms, it has remained challenging to determine which transitions occur and at what rates without pertur...

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Detalles Bibliográficos
Publicado en:Cell Syst
Main Authors: Hormoz, Sahand, Singer, Zakary S., Linton, James M., Antebi, Yaron E., Shraiman, Boris I., Elowitz, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142829/
https://ncbi.nlm.nih.gov/pubmed/27883889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.10.015
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