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Inferring cell state transition dynamics from lineage trees and endpoint single-cell measurements

As they proliferate, living cells undergo transitions between specific molecularly and developmentally distinct states. Despite the functional centrality of these transitions in multicellular organisms, it has remained challenging to determine which transitions occur and at what rates without pertur...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Hormoz, Sahand, Singer, Zakary S., Linton, James M., Antebi, Yaron E., Shraiman, Boris I., Elowitz, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142829/
https://ncbi.nlm.nih.gov/pubmed/27883889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.10.015
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