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Lysine-Specific Demethylase 1 (LSD1) Inhibitor S2101 Induces Autophagy via the AKT/mTOR Pathway in SKOV3 Ovarian Cancer Cells
BACKGROUND: S2101 is one of the most potent LSD1 inhibitors, which can inhibit ovarian cancer cells viability. This study aimed to detect the mechanism behind the anticancer properties of S2101 in SKOV3 ovarian cells. MATERIAL/METHODS: Cell viability was tested by Cell Counting Kit-8 (CCK-8) assay....
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| Izdano u: | Med Sci Monit |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
International Scientific Literature, Inc.
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142589/ https://ncbi.nlm.nih.gov/pubmed/27914215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.898825 |
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