Transcriptome profiling in oral cavity and esophagus tissues from (S)-N′-nitrosonornicotine-treated rats reveals candidate genes involved in human oral cavity and esophageal carcinogenesis

Recently, we have shown that (S)-N′-Nitrosonornicotine [(S)-NNN], the major form of NNN in tobacco products, is a potent oral cavity and esophageal carcinogen in rats. To determine the early molecular alterations induced by (S)-NNN in the oral and esophageal mucosa, we administered the carcinogen to...

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Publicado en:Mol Carcinog
Autores principales: Khammanivong, Ali, Anandharaj, Arunkumar, Qian, Xuemin, Song, Jung Min, Upadhyaya, Pramod, Balbo, Silvia, Bandyopadhyay, Dipankar, Dickerson, Erin B., Hecht, Stephen S, Kassie, Fekadu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142294/
https://ncbi.nlm.nih.gov/pubmed/26785143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22459
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