Increased Th2 activity and diminished skin barrier function cooperate in allergic skin inflammation

Atopic dermatitis (AD) is a chronic inflammatory skin disease induced by a complex interaction between susceptibility genes encoding skin barrier components and environmental allergen exposure that results in type 2 cytokine production. Although genetic lesions in either component can be risk factor...

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Bibliografske podrobnosti
izdano v:Eur J Immunol
Main Authors: Sehra, Sarita, Krishnamurthy, Purna, Koh, Byunghee, Zhou, Hong-Ming, Seymour, Lee, Akhtar, Nahid, Travers, Jeffrey B., Turner, Matthew J., Kaplan, Mark H.
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142240/
https://ncbi.nlm.nih.gov/pubmed/27510401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646421
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