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IL-4 regulates skin homeostasis and the predisposition towards allergic skin inflammation
IL-4 promotes the development of Th2 cells and allergic inflammation. In Atopic Dermatitis (AD) lesions, IL-4 decreases the expression of multiple genes associated with innate defense including genes in the epidermal differentiation complex (EDC) that regulate epidermal barrier function. However, it...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837507/ https://ncbi.nlm.nih.gov/pubmed/20147633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901860 |
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