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IL-4 regulates skin homeostasis and the predisposition towards allergic skin inflammation

IL-4 promotes the development of Th2 cells and allergic inflammation. In Atopic Dermatitis (AD) lesions, IL-4 decreases the expression of multiple genes associated with innate defense including genes in the epidermal differentiation complex (EDC) that regulate epidermal barrier function. However, it...

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Bibliografiske detaljer
Main Authors: Sehra, Sarita, Yao, Yongxue, Howell, Michael D., Nguyen, Evelyn T., Kansas, Geoffrey S., Leung, Donald Y. M., Travers, Jeffrey B., Kaplan, Mark H.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837507/
https://ncbi.nlm.nih.gov/pubmed/20147633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901860
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