Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells

Epidemiological studies support strong links between obesity, diabetes, and pancreatic disorders including pancreatitis and pancreatic adenocarcinoma (PDAC). Type 2 diabetes (T2DM) is associated with insulin resistance, hyperglycemia, and hyperinsulinemia, the latter due to increased insulin secreti...

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Bibliographic Details
Published in:Am J Physiol Gastrointest Liver Physiol
Main Authors: Yang, Jiayue, Waldron, Richard T., Su, Hsin-Yuan, Moro, Aune, Chang, Hui-Hua, Eibl, Guido, Ferreri, Kevin, Kandeel, Fouad R., Lugea, Aurelia, Li, Ling, Pandol, Stephen J.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
Subjects:
Pancreatic Physiology/Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142202/
https://ncbi.nlm.nih.gov/pubmed/27609771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00251.2016
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