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CaMKII-dependent phosphorylation regulates basal cardiac pacemaker function via modulation of local Ca(2+) releases
Spontaneous beating of the heart pacemaker, the sinoatrial node, is generated by sinoatrial node cells (SANC) due to gradual change of the membrane potential called diastolic depolarization (DD). Spontaneous, submembrane local Ca(2+) releases (LCR) from ryanodine receptors (RyR) occur during late DD...
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| Gepubliceerd in: | Am J Physiol Heart Circ Physiol |
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| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Physiological Society
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142178/ https://ncbi.nlm.nih.gov/pubmed/27402669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00765.2015 |
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