“Gap hunting” to characterize clustered probe signals in Illumina methylation array data

BACKGROUND: The Illumina 450k array has been widely used in epigenetic association studies. Current quality-control (QC) pipelines typically remove certain sets of probes, such as those containing a SNP or with multiple mapping locations. An additional set of potentially problematic probes are those...

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Udgivet i:Epigenetics Chromatin
Main Authors: Andrews, Shan V., Ladd-Acosta, Christine, Feinberg, Andrew P., Hansen, Kasper D., Fallin, M. Daniele
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142147/
https://ncbi.nlm.nih.gov/pubmed/27980682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0107-z
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