Učitavanje...
The biological effects and clinical implications of BRCA mutations: where do we go from here?
BRCA1 and BRCA2 are tumour-suppressor genes encoding proteins that are essential for the repair of DNA double-strand breaks by homologous recombination (HR). Cells that lack either BRCA1 or BRCA2 repair these lesions by alternative, more error-prone mechanisms. Individuals carrying germline pathogen...
Spremljeno u:
| Izdano u: | Eur J Hum Genet |
|---|---|
| Glavni autor: | |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5141575/ https://ncbi.nlm.nih.gov/pubmed/27514841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.93 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|