Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development

Notch1 signaling plays a critical role in maintaining and determining neural stem/progenitor cell (NSPC) fate, yet the transcriptional mechanism controlling Notch1 specific expression in NSPCs remains incomplete. Here, we show transcription factor Nkx6.1 interacts with a cis-element (CR2, an evoluti...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Li, Ying, Tzatzalos, Evangeline, Kwan, Kelvin Y., Grumet, Martin, Cai, Li
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141430/
https://ncbi.nlm.nih.gov/pubmed/27924849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38665
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