The activation domain of the bovine papillomavirus E2 protein mediates association of DNA-bound dimers to form DNA loops.
The E2 transactivator protein of bovine papillomavirus binds its specific DNA target sequence as a dimer. We have found that E2 dimers, preformed in solution independent of DNA, exhibit substantial cooperativity of DNA binding as detected by both nitrocellulose filter retention and footprint analysi...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1991
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51414/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1849647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.8.3204 |
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