Lymphocytes as cellular vehicles for gene therapy in mouse and man.
The application of bone marrow gene therapy has been stalled by the inability to achieve stable high-level gene transfer and expression in the totipotent stem cells. We show that retroviral vectors can stably introduce genes into antigen-specific murine and human T lymphocytes in culture. Murine hel...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2014235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.8.3155 |
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