Lymphocytes as cellular vehicles for gene therapy in mouse and man.

The application of bone marrow gene therapy has been stalled by the inability to achieve stable high-level gene transfer and expression in the totipotent stem cells. We show that retroviral vectors can stably introduce genes into antigen-specific murine and human T lymphocytes in culture. Murine hel...

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Bibliografiske detaljer
Main Authors: Culver, K, Cornetta, K, Morgan, R, Morecki, S, Aebersold, P, Kasid, A, Lotze, M, Rosenberg, S A, Anderson, W F, Blaese, R M
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC51404/
https://ncbi.nlm.nih.gov/pubmed/2014235
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