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High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes.

Peripheral blood lymphocytes (PBLs) are primary targets for gene therapy of inherited and acquired disorders of the immune system. We describe the development of an optimized transduction system that provides for high-efficiency retrovirus-mediated gene transfer into primary PBLs. This optimized tra...

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Detalhes bibliográficos
Main Authors: Bunnell, B A, Muul, L M, Donahue, R E, Blaese, R M, Morgan, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC41221/
https://ncbi.nlm.nih.gov/pubmed/7644487
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