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Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study

Several candidate vaccines against Shigella spp. are in development, but the lack of a clear correlate of protection from challenge with the induction of adequate immune responses among the youngest age groups in the developing world has hampered Shigella vaccine development over the past several de...

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Vydáno v:Clin Vaccine Immunol
Hlavní autoři: Riddle, Mark S., Kaminski, Robert W., Di Paolo, Claudio, Porter, Chad K., Gutierrez, Ramiro L., Clarkson, Kristen A., Weerts, Hailey E., Duplessis, Christopher, Castellano, Amy, Alaimo, Cristina, Paolino, Kristopher, Gormley, Robert, Gambillara Fonck, Veronica
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139601/
https://ncbi.nlm.nih.gov/pubmed/27581434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00224-16
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