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Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting.

Recently it has become possible to introduce predesigned mutations into a given gene in the mouse germ line by homologous recombination in embryonic stem cells. The mutations are usually introduced by inserting the neomycin phosphotransferase gene into an exon of a particular gene. Here we describe...

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Detaylı Bibliyografya
Asıl Yazarlar: Mombaerts, P, Clarke, A R, Hooper, M L, Tonegawa, S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1991
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC51389/
https://ncbi.nlm.nih.gov/pubmed/1826563
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