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Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains

The Cag Type IV secretion system, which contributes to inflammation and cancerogenesis during chronic infection, is one of the major virulence factors of the bacterial gastric pathogen Helicobacter pylori. We have generated and characterized a series of non-marked site-directed chromosomal mutants i...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Bönig, Tobias, Olbermann, Patrick, Bats, Simon H., Fischer, Wolfgang, Josenhans, Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138618/
https://ncbi.nlm.nih.gov/pubmed/27922023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38101
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