Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains

The Cag Type IV secretion system, which contributes to inflammation and cancerogenesis during chronic infection, is one of the major virulence factors of the bacterial gastric pathogen Helicobacter pylori. We have generated and characterized a series of non-marked site-directed chromosomal mutants i...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Bönig, Tobias, Olbermann, Patrick, Bats, Simon H., Fischer, Wolfgang, Josenhans, Christine
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138618/
https://ncbi.nlm.nih.gov/pubmed/27922023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38101
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