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The subcellular organization of UBE3A in neurons

Ubiquitination regulates a broad array of cellular processes, and defective ubiquitination is implicated in several neurological disorders. Loss of the E3 ubiquitin-protein ligase UBE3A causes Angelman syndrome. Despite its clinical importance, the normal role of UBE3A in neurons is still unclear. A...

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發表在:J Comp Neurol
Main Authors: Burette, Alain C., Judson, Matthew C., Burette, Susan, Phend, Kristen D., Philpot, Benjamin D., Weinberg, Richard J.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138109/
https://ncbi.nlm.nih.gov/pubmed/27339004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.24063
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