Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation

Motivated reward-seeking behaviours are governed by dopaminergic ventral tegmental area projections to the nucleus accumbens. In addition to dopamine, these mesoaccumbal terminals co-release other neurotransmitters including glutamate and GABA, whose roles in regulating motivated behaviours are curr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Berrios, Janet, Stamatakis, Alice M., Kantak, Pranish A., McElligott, Zoe A., Judson, Matthew C., Aita, Megumi, Rougie, Marie, Stuber, Garret D., Philpot, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754338/
https://ncbi.nlm.nih.gov/pubmed/26869263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10702
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