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TIF-IA: an oncogenic target of pre-ribosomal RNA synthesis
Cancer cells devote the majority of their energy consumption to ribosome biogenesis, and pre-ribosomal RNA transcription accounts for 30–50% of all transcriptional activity. This aberrantly elevated biological activity is an attractive target for cancer therapeutic intervention if approaches can be...
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| Publicat a: | Biochim Biophys Acta |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5138081/ https://ncbi.nlm.nih.gov/pubmed/27641688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2016.09.003 |
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