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MicroRNA-497 Induces Apoptosis and Suppresses Proliferation via the Bcl-2/Bax-Caspase9-Caspase3 Pathway and Cyclin D2 Protein in HUVECs

INTRODUCTION: MicroRNAs play crucial roles in various types of diseases. However, to date, no information about the role of miR-497 in the development of atherosclerosis has been reported. This study investigated the possible role of miR-497 in vascular endothelial cell injury during the early stage...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wu, Ridong, Tang, Shi, Wang, Mian, Xu, Xiangdong, Yao, Chen, Wang, Shenming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137897/
https://ncbi.nlm.nih.gov/pubmed/27918592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167052
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